Our research focuses on understanding the fundamental properties
of information coding in the nervous system.
How do neuronal networks efficiently encode information, given
the great amount of redundancy in natural statistical inputs?
How do neuronal networks predict the future?
What are the codewords composing the neural dictionary? Does the
brain use spike timing to encode information?
How do priors and expectations shape the encoding of sensory
How do neural networks learn things in an unsupervised way?
How does neural processing depend on brain state?
To answer these kind of questions, we use a variety of
techniques and approaches.
machine learning techniques to model predictive
relationships among sensory inputs - across space and time.
We develop new algorithms for unsupervised clustering of
high-dimensional neural datasets.
We use information and neural network theory to understand
We use high-density, multi-areal electrophysiological
recordings of neurons, from all cortical layers.
We use optogenetics to identify subtypes of neurons - like
interneurons - and modify cortical activity.
For example we are manipulating top-down pathways using new
opsins and AAV viruses.
We carefully monitor the state of the organism using e.g.
And we never forget about dynamics, chaos and synchronization,
as the brain is an analog computing system.
Dynamics can solve computational problems in unthinkable ways.
We are always looking for talented master students, PhD
candidates and postdocs to join our team.
We hire people with a variety of backgrounds such as biology
and computer science.
Frankfurt is an extremely exciting neuroscience hub, with
several Max Planck institutes for Neuroscience.
And, some great university research centers nearby.
Our institute is brand-new and close to the center and
beautiful river area.
Also check out the IMPRS program for neural circuits if you
want to do a PhD.
ESI has excellent working conditions and salaries for PhDs and
Please contact me at firstname.lastname@example.org
We thank the Struengmann brothers for their continuous and
generous support for research.