Research Group Leader at Ernst
Struengmann Institute for Neuroscience in Cooperation with
Max Planck Society
2018, Paper accepted
M.*, Vinck, M.*, Pant, R., Cardin,
activity precedes ictal onset.
We used optogenetics and
electrophysiology to record from
specific GABAergic interneurons in
the hippocampus before and during
The hippocampus is the main focus
where seizures originate, and
inhibition is thought to play a
critical role in the generation of
The reason for this is that
inhibition plays a critical role in
stabilizing network dynamics and
balancing recurrent excitatory
We used optogenetics to identify
specific identified GABAergic
interneurons, and tracked their
activity before and during seizures.
Surprisingly, we found a very strong
increase in the firing of a specific
interneuron (PV interneuron) right
before the seizure.
In addition, we found that their
activity becomes decoupled from the
excitatory cell activity.
These PV interneurons are thought to
play a critical role in network
These data suggest that an increase
in their activity together with
decoupling from excitatory neurons
the destabilization of network
activity and epileptic seizures.
My old colleague Jeroen Bos
got his PhD at the University of Amsterdam.
Congratulations, Jeroen! It was great fun working
together with you. Any lab will be lucky to have
Jeroen for postdoc.
Jeroen's thesis (some parts under embargo) can be
found at the UvA
Including some nice unpublished work we did together
on how the brain represents other agents.
Our postdoc Ana made some
beautiful simultaneous recordings from multiple areas
and layers together with optogenetics..
And PhD student Irene tagging multiple SOM
September 2018, Berlin
We will be at Bernstein Computational Neuroscience
Meeting in Berlin. Cem is presenting. Fantastic workshops
Very interesting predictive coding session, good to see
these ideas are still alive and relevant.
Also amazing talk from James DiCarlo.
Lots of cool development in recurrent neural networks.
September 2018: Looking for
PhD and master students
We are looking for multiple PhD students to work on big
data projects on developing new algorithms and software for
high-dimensional neural datasets.
Come join vibrant lab with experimental and theoretical work
in Germany's neuroscience hub!
Also looking for master students.
September 2018: Paper posted on Biorxiv
Peter, A.*, Uran, C*,
Klon-Lipok, J, Roese, R., van Stijn, S., Barnes, W.,
Dowdall, J, Singer, W, Fries, P, Vinck, M. Surface
color and predictability determine contextual modulation
of V1 firing and gamma oscillations. 2018.
Result of a great collaboration with Fries and Singer labs,
and amazing PhD students Alina and Cem. Six different
nationalities on this paper, and some
29-31st August 2018:
We had a great "ESI-Sync 2018" meeting. Thanks Miriam,
Ana, Maestro Andre and Nina.
I especially enjoyed Floris de Lange's talk, a creative
thinker with great conceptual depth, and I was impressed
what he extracts from neuroimaging methods!
Keep an eye on 2019!
August 2018: Paper in Current Opinion Neurobiology
Batista-Brito*, R, Zagha*, E, Ratliff, J., Vinck, M*. Modulation
of cortical circuits by top-down processing and arousal
state in health and disease. Current Opinion in
Paper with some good old friends from the Yale and gpscy
times. Interneuron mechanisms of top-down attention and
state modulation and how it might be messed up in
psychiatric diseases like schizophrenia.
July 2018: Paper accepted in Plos Computational Biology
Grossberger, L., Battaglia, F., Vinck, M. Unsupervised clustering of temporal patterns in
high-dimensional neuronal ensembles using a novel
dissimilarity measure. PLOS
Amazing work from master student Lukas, and long
collaboration with Fra. Too bad Lukas declined IMPRS offer
and got hired by Bosch Machine Learning group...but he will
build some pretty mean machines :)
July 2018: FENS, Berlin
Great FENS meeting, and good to see some old friends.
June 2018: Paper accepted in Nature
Pesaran, B. Vinck, M., Einevoll, G.,
Sirota, A., Fries, P., Siegel, M., Truccolo, W.,
Schroeder, C., Srinivasan, R. 2018. Investigating
large-scale brain dynamics using field
potential recordings: Analysis and
interpretation. Nature Neuroscience
Useful piece for advanced graduate students who wants
to learn more about interpreting and analyzing brain data.
Thanks to Bijan for organizing this and giving room to